Archive for December, 2015

iPS Study of Family Members Discordant for ADHD

December 12, 2015

Recruiting Subjects

Currently recruiting pairs of subjects consisting of an adult (18 – 40 years of age) with ADHD plus an adult same-sex blood relative without ADHD or other psychiatric disorders for a very interesting study.  Participants with ADHD can be on or off medications.  The study involves comprehensive assessment and testing plus collection of a small skin sample. The skin sample will be cultured, converted into induced pluripotent stem cells (a very complex process), and the stem cells transformed into dopamine neurons.  We will then compare dopamine neurons of participants with ADHD to dopamine neurons from family members without ADHD. Subjects will be paid $75 for their participation. If you are interested and would like some more information, please call Cindy at (617) 855-2973 or email cmcgreenery@mclean.harvard.edu

 

For more about induced Pluripotent Stem Cells – see:

Robinton, D.A. and G.Q. Daley, The promise of induced pluripotent stem cells in research and therapy. Nature, 2012. 481(7381): p. 295-305

Bellin, M., et al., Induced pluripotent stem cells: the new patient? Nat Rev Mol Cell Biol, 2012. 13(11): p. 713-26.

Childhood Maltreatment Changes Cortical Network Architecture and May Raise Risk for Substance Use

December 7, 2015

An article, by Scott Eddie, highlighting our work on this topic  has been published in NIDA Notes.  I’ve attached the link. NIDA Notes Article